Description
IPRAFEINE contains two active substances: ibuprofen and caffeine. Ibuprofen belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs provide relief by changing the way the body responds to pain and fever.
Caffeine belongs to a group of medicines called stimulants.
IPRAFEINE is used for the short-term treatment of acute pain of moderate intensity.
IPRAFEINE is only indicated for adults.
Using advice
Always take this medicine exactly as described in this leaflet or by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist for advice.
The recommended dose is:
Adults:
Starting dose: take 1 tablet (400 mg ibuprofen and 100 mg caffeine). If needed, take an additional dose (one tablet) but do not exceed a total dose of 1200 mg ibuprofen and 300 mg caffeine (3 tablets) over a 24 hour period. The interval between two doses should be at least 6 hours.
Talk to your doctor or pharmacist if you have the impression that the effect of this medicine is too strong or too weak.
Oral route.
Swallow the tablets whole with a glass of water.
The duration of treatment should not exceed 3 days.
IPRAFEINE is not recommended for mild pain or when the duration of treatment exceeds 3 days. Consult your doctor or pharmacist if the pain persists.
Composition
The active substances are ibuprofen and caffeine:
Each film-coated tablet contains 400 mg of ibuprofen and 100 mg of caffeine.
The other ingredients are:
Tablet core:
Microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate.
Lamination:
Hypromellose, hyprolose, macrogol 6000, talc, titanium dioxide (E171).
Precautions for use
You should avoid consuming large amounts of caffeinated products (for example, coffee, tea, food, other medicines, and drinks) with IPRAFEINE.
The occurrence of side effects can be minimized by using the lowest effective dose for the shortest time possible. Elderly patients are at increased risk of side effects.
Concomitant use of NSAIDs, including specific cyclooxygenase 2 inhibitors, increases the risk of side effects (see section “Other medicines and IPRAFEINE 400 mg / 100 mg film-coated tablets”) and should be avoided.
Anti-inflammatory / painkiller medicines such as ibuprofen may be associated with a slight increased risk of heart attack or stroke, especially with high dose use. Do not exceed the recommended dose or duration of treatment (3 days).
Pregnancy and breast feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Tell your doctor if you get pregnant while taking IPRAFEINE. Do not take this medicine during the last 3 months of pregnancy. Avoid using this medicine during the first 6 months of pregnancy unless your doctor tells you otherwise.
The active substances, ibuprofen and caffeine, pass into breast milk. Irritability and sleep disturbances have been reported in breastfed children. IPRAFEINE should only be used by nursing mothers if clearly needed.
The product belongs to a group of drugs (NSAIDs) which may impair fertility in women. This effect is reversible when the drug is stopped.
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