Indication Fixical 500mg/400UI Vitamin D3 is for: - those with a calcium and vitamin D deficiency - a supplement to osteoporosis treatments when the intake of calcium and vitamin D is not sufficient. How to take Fixical 500 How to use Orally. Chew or suck tablet then drink a glass of water. Take the tablet outside of mealtimes. Dosage Only to be used by adults. The daily dose is 2 tablets per day (1 in the morning, 1 in the evening). YOU MUST COMPLY WITH THE PRESCRIPTION GIVEN FROM YOUR DOCTOR. Length of treatment YOU MUST COMPLY WITH THE PRESCRIPTION GIVEN FROM YOUR DOCTOR. Composition What is in the Fixical 500 tablet? Active substances are (per tablet): Calcium carbonate at 90%: 1387.50 mg Quantity of calcium: 500.00 mg Coated cholecalciferol at 100,000 UI/g (vitamin D, 100, CWS)**: 4.00 mg Quantity of cholecalciferol: 400 UI *Mixture of calcium carbonate at 90% and wheat starch. **Mixture of cholecalciferol, alphatocopherol, fatty foods, gelatine, saccharose and wheat starch. Other ingredients: Sorbitol, aspartame, lemon flavouring (lemon essential oil, ascorbic acid, citral, maltodextrin, saccharose), magnesium stearate. Format of FIXICAL VITAMIN D3 500mg/400UI This drug is in the form of a tablet to be chewed or sucked. Box of 60. Precautions for use Use this medication WITH PRECAUTION in the case of: · Prolonged treatment, it is important to have regularly check the quantity of calcium eliminated in the urines (calciuria). Depending on the outcome, your doctor may have to reduce or even stop your treatment, · Supplementary administration of calcium and vitamin D at high doses which must be done under strict medical supervision. · When taking bisphosphonates, it is advisable to wait at least two hours between taking these medicines and FIXICAL Vitamin D3, as well as in case of treatment with an antibiotic belonging to the cyclin family. · In case of sarcoidosis or renal insufficiency. IF IN DOUBT DO NOT HESITATE TO CONSULT YOUR DOCTOR OR PHARMACIST FOR ADVICE. Contraindications Do not take FIXICAL 500mg/400UI tablet in the following cases: · allergy to one of its components, · hypercalcemia (abnormally high level of calcium in the blood) · hypercalciuria (high level of calcium in the urine) · kidney stones · if you suffer from phenylketonuria (a hereditary disease discovered at birth) due to the aspartame content. IF IN DOUBT IT IS ADVISABLE TO ASK YOUR DOCTOR OR PHARMACIST FOR ADVICE. Pregnancy and breast feeding During pregnancy do not exceed 1500mg of calcium and 600UI of vitamin D3 per day (1 tablet). During pregnancy and breast feeding it is always recommended to consult your doctor or pharmacist before taking any type of drug.